Consultative medicine (click to go to the specific page to find out more):
The Angeles Clinic and Research Institute Center for Immuno-Oncology conducts clinical trials for a variety of cancers using immunotherapy. If you are interested in participating in a clinical trial, specialists from our Center will work with you and your current treatment team to discuss whether immunotherapy may be an option for you.
- Research and Clinical Trials - Progress made through trials
- See a list of current clinical trials. Are you eligible? Find out here
Immuno-Oncology
Paradigm-shifting therapy for all solid tumors.Immunotherapy, specifically immune checkpoint inhibitors targeting CTLA4, and the PD-1/PD-L1 pathway, have taken center stage at recent international and national oncology meetings. Data from these paradigm-shifting therapies, initially beneficial in melanoma and renal (kidney) cancers, have shown remarkable initial efficacy in other solid tumors ; lung, ovarian and a host of other carcinomas.
As one of the most exciting areas of cancer research today, Immuno-oncology unleashes the power of the body's immune system to detect and combat tumors in a custom tailored fashion. Our Immuno-Oncology Center aims to maximize the advances of immunotherapy and take advantage of growing enthusiasm in the field, spurred by recent successes to bring these benefits to all of our patients with a wide range of cancers. The Center fosters collaborative research among laboratory and clinical investigators in many different departments at The Angeles Clinic and Research Institute.
The Angeles Clinic and Research Institute has been involved with PD-1/PD-L1 antibodies since their inception. We were amongst the first to make the drug deemed by the FDA to be a “breakthrough” therapy, Pembrolizumab (MK-3475), available for patients. This data was presented and simultaneously published in the New England Journal of Medicine (Hamid et al.). Our very own Omid Hamid, MD presented ground breaking data with anti-PDL1 antibody MPDL328A in melanoma.
Our clinical trials program currently builds on this promise towards combinations to overcome PD1 resistance and set standards for solid tumors and lymphomas
Phase 1 Clinical Program expands at The Angeles Clinic Success developing targeted therapies in oncology depends on the ability to identify new targets and develop agents that hit those targets in an efficient manner. Major clinical advances in the care of common cancers have been made through participation of patients in Phase I clinical trials of agents that achieve this goal. Predictive oncology biomarkers - i.e., genes and genetic mutations, proteins and signalling pathways implicated in the proliferation and death of cancer cells - and their use to control tumor growth has been a major advancement allowing more efficacious therapy with decreased toxicity. Our collaboration with pharmaceutical partners has been instrumental in bringing this care to our patients.
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Endocrinology - is a specialty within medicine that focuses on the system of hormones and the treatment of
related diseases affecting the body. Some of the more commonly known endocrine system diseases are Diabetes,
Thyroid Disorders and Grave’s Disease to name a few.
Endocrine disorders may arise on their own and are sometimes related to a cancer diagnosis. Treatment for
these diseases varies depending on your own unique clinical circumstances and may include a need for
therapies such as insulin, dietary modifications, exercise, physical medicine and rehabilitation, and even surgery in some
cases.
The Angeles Clinic and Research Institute is home to physicians and clinical staff who not only specialize
in the field of Endocrinology but are internationally renowned in the field allowing us to offer premier
diagnosis and treatment options for our patients. Artak Labadzhyan, MD MD serves as our Chief
Endocrinologist at TACRI, he is board certified in Internal Medicine, Endocrinology, Diabetes and
Metabolism. His research is cutting edge and focused on the causes of pituitary cancers, their diagnosis and
treatment options.
At The Angeles Clinic and Research Institute we are able to offer our patients access to expert physicians
and clinical services for the most advanced cases of Endocrine disease. No matter how complex or simple your
case may be, our suite of services is available in one location giving you the opportunity to focus on your
care and healing without the worry of travelling to multiple locations.
Whether you are a current patient or seeking an appointment with a specialist here for the first time, our
staff is ready to assist. Please contact at: (310) 231-2121
or use our secure online appointment request
form to schedule an appointment at The Angeles Clinic and Research Institute.
- NanoKnife: A new device used to send electricity through a tumor to destroy cancerous tissue under the guidance of a CT scan.
- Focal Cryoablation: Using a very small needle a solution is injected around the tumor causing it to freeze and destroy the cancerous tissue while preserving the healthy surrounding areas of the prostate.
- High-intensity Focused Ultrasound (HIFU): This method is one of the least invasive treatment options available for prostate cancer. Soundwaves are focused and passed through the tumor under the guidance of an MRI allowing the ability to visualize the destruction of the tumor in real time. This method is becoming more attractive to patients as it has very few side effects and there is little to no discomfort involved during the procedure.
- Photodynamic Therapy: This method is currently a clinical trial that involves the injection of a drug through very small fibers that are placed within the prostate. The drug then reacts to a specially colored light causing the destruction of the cancerous tissue where it was placed.
The follow up course of care after focal therapy includes assessing your physical recovery following the procedure, laboratory work to trend your Prostate Surface Antigen levels (PSA blood test) and additional imaging to visualize the elimination of the tumor and quality of the remaining prostate tissue. Should the cancer return or any other problems arise our team of expert Urologists, Surgeons and Clinical staff are able to offer multiple treatment options following Focal Therapy.
Whether you are a current patient or seeking an appointment with a specialist here for the first time, our staff is ready to assist.
Our approach to Pain Management includes:
- Assessment of Pain
- Pain Medications
- Physical Medicine & Rehabilitation
- Psychosocial Support
- Radiation Therapy
- Invasive Procedures
- Evaluation of efficacy
- Tailoring of the approach throughout your care
- Palliative care and comfort measures for End of Life Care
You and your doctor will plan for your own pain management and our team is on call 24/7 should you need anything while under our care.
Program
Olivia Tan MS, CGC leads the Genetic Counseling services at The Angeles Clinic and Research Institute, she is certified by the American Board of Genetic Counseling and licensed by the California Department of Public Health. Olivia has been practicing as an Oncology Genetic Counselor since 2013. She received her Bachelor of Science degree in Microbiology from North Carolina State University and her Master of Science degree in Human Genetics from Sarah Lawrence College.
Initial appointments generally last an hour and during this time you will review your personal and/or family history of cancer, and the genetic counselor will evaluate for the possibility of a hereditary cancer syndrome. As a part of a genetic counseling consultation, genetic testing may be done, which consists of a blood test or saliva sample to allow for a comprehensive analysis of your own genetic risk factors. Hereditary genetic testing is an important step in the therapy care plan for many individuals with a cancer diagnosis and can guide cancer screening and prevention for individuals without cancer. Whether you have a new diagnosis of cancer or are concerned about your risk factors for developing cancer, Genetic Counseling offers a compassionate setting to meaningfully discuss your health and provide an understanding of your own individual risk for disease.
Scheduling
In order to receive genetic counseling services at TACRI your Oncologist and clinical team may make a referral on your behalf or you may contact the scheduling office to make an appointment. This service is available to both current patients and new patients with or without a referral from your physician.
Genetic Counseling for Hereditary Cancer Risk
We now are pleased to announce the addition of Genetic Counseling for Hereditary Cancer Risk at The Angeles Clinic and Research Institute. The Angeles Clinic and Research Institute brings patients and expert healthcare providers together in a clinical program that is recognized as the premier center for the comprehensive treatment of all states of cancer.
Evaluation for a possible hereditary cancer syndromes is an important step in the surgical and/or oncologic care plan for many individuals with a cancer diagnosis and can guide cancer screening and prevention for individuals without cancer.
The Angeles Clinic and Research Institute offers on-site genetic counseling by a board-certified and licensed genetic counselor who can:
- Review a patient’s personal and/or family history of cancer
- Perform risk assessment for hereditary cancer syndromes
- Determine the most appropriate genetic test(s) and the most informative approach to genetic testing for patients and/or their families
- Coordinate genetic testing and insurance authorizations
- Interpret genetic test results, review syndrome inheritance, and identify relatives who may benefit from genetic testing
- Help patients and their physicians understand and apply genetic test results to medical management decisions based upon associated cancer risks
- Offer patients and their relatives counseling and emotional support
Genetic testing can be performed on either a blood or saliva sample. Results are typically available within three weeks and these are discussed during an in-person follow-up visit.
Whether you are a current patient in need of a consultation or a new patient looking to meet with a surgeon in the Los Angeles area, please feel free to contact us and our staff can set up an appointment for you at your earliest convenience. Please contact at: (310) 231-2121 or use our secure online appointment request form to schedule an appointment at The Angeles Clinic and Research Institute.
We understand nutrition impacts all cancer types and treatments, including radiation, chemotherapy, immunotherapy and surgery. Our dietitians can customize a cancer patient's nutrition care, never losing sight of their individual needs and treatment goals.
Clinical Nutrition Services for Cancer Patients Include:
- Guidance for optimal nutrition before and during treatment
- Management of treatment-related side effects impacting nutrition or eating
- Use of vitamins, minerals and herbal supplements
- Meal planning for cancer-related weight control
- Support in managing enteral (feeding tube) and parenteral (intravenous, or through the vein) nutrition
- Healthy lifestyle and nutrition choices for cancer prevention, recovery and survivorship
Clinical Nutrition Coordinator–Supervisor
Arlene Provisor, MHA, RD, CSO, CNSC
Nourishing our bodies for strength and energy is critical at every stage of our lives. For our patients, even the slightest changes in dietary choices and timing can dramatically impact their ability to reach their nutrition goals.

Following a visit with your doctor if imaging or radiology services are required, they can be performed right here where your treatment is already being provided and results/reporting are generally ready for review around one hour after completion. Appointments may vary in duration depending on the type of service being provided.
We currently offer the Radiology services of:
- Positron Emission Tomography (PET)
- SPECT-Computed Tomography (SPECT-CT)
- Nuclear Therapeutics
- Radiofrequency Ablation (RFA)
A positron emission tomography (PET) scan is an imaging test that helps measure how your tissues and organs are functioning. A PET scan uses a radiopharmaceutical or tracer to show this activity. This scan can provides a high degree of accuracy and precision and may sometimes detect disease before it shows up on other types of imaging tests.
The most advanced form of CT scanning available and one of only 3 SPECT-CT machines in the Los Angeles area. A SPECT-CT scan is a type of nuclear medicine scan where the images or pictures from two different types of scans are combined together. The combined scan can provide precise information about how different parts of the body are working and more clearly identify problems.
SPECT CT scans allow for images to be captured with the highest degree of precision when compared to conventional cameras and allows for nuclear medicine services to be administered with the greatest level of accuracy.
The administration of radiopharmaceuticals for diagnostic or treatment related purposes, nuclear therapeutics involves the administration of radioisotopes as either an implant or injection. Your Oncologist will work with you and the radiology team at TACRI to determine the most appropriate treatment course should your clinical presentation meet the criteria to benefit from nuclear therapeutic services.
Radiofrequency Ablation is a process that involves the use of a needle to travel underneath the skin to nerve endings in an attempt to destroy nerves or clusters of cancerous cells connected to a particular area of the body. This therapy is useful in the management of pain for cancer patients who require pain management beyond what pharmaceuticals are able to offer and is an effective method for treating and even removing cancer from the body.
- The potential cure for liver metastases associated with metastatic colorectal cancer
- Lung cancer
- Renal cancer and adrenal gland cancer
- An alternative to more invasive surgical procedures
- Effective method for lasting chronic pain management that is non narcotic and relieving of the pain associated with chemotherapy, radiation therapy and cancer itself.
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Tumor tracking
Tumor tracking is a trend type measurement used to evaluate changes in tumors throughout the course of therapy for oncology patients. Multiple diagnostic tools are available to provide the measurements necessary to determine cancer progression. This allows for accurate, individualized and informed decision making between you and your provider.
- Interventional and Vascular Radiology
Interventional radiology is a subspecialty of radiology where image-guided procedures are performed to diagnose and treat diseases involving multiple organ systems and the vasculature. Using the least invasive techniques currently available these procedures are precision based and have less risk, less pain and less recovery time when compared to general surgery.
- Musculoskeletal imaging
Musculoskeletal imaging is a subspecialty of radiology involving the interpretation of images of bones, joints and associated soft tissues and diagnosing injuries and disease.
- X-Ray
An X-ray is a quick, photograph-like test that produces images of the bones inside your body using small amounts of radiation called X-rays. During the test, X-ray beams pass through your body, and they are absorbed in different amounts depending on the material. X-ray imaging is able to allow for the evaluation and interpretation of bones, fat, foreign objects and air within the body.
For some types of X-ray tests, a contrast medium — such as iodine or barium — may be administered to provide a higher quality accuracy and detail. - MRI
Magnetic resonance imaging (MRI) is an imaging method which uses a magnetic field and radio waves to build detailed images of the organs and tissues within your body.
MRI machines are commonly large tubes which hold very strong magnets. Patients lie down on a bench which is then slid inside the tube, while inside the magnetic field temporarily moves water within your body while the administration of radio waves allow for images to be taken and compiled into highly accurate 3D renderings of the inside of your body.
We are able to medicate and monitor patients with a history of claustrophobia and anxiety during the MRI procedure when necessary. - Ultrasound
Ultrasound is the generation of images by using the reflection of soundwaves off of the soft tissues that make up your body. Ultrasound procedures are not painful, require little or no preparation and involve the simple application of a gel on top of the area being examined.
Same day testing may be available and results of imaging may be ready in as little as one hour following your appointment.


Consultative medicine